cis-tert-butyl (7,7-difluorobicyclo[4.1.0]heptan-3-yl)carbamate - Names and Identifiers
cis-tert-butyl (7,7-difluorobicyclo[4.1.0]heptan-3-yl)carbamate - Introduction
cis-tert-butyl (7,7-difluorobicyclo[4.1.0]heptan-3-yl)carbamate is an organic compound whose chemical structure contains 7, the structural group of 7-difluorobicyclo[4.1.0] heptyl-3-yl.
Properties of the compound include:
-Appearance: colorless liquid
-molecular formula: C12H16F2N2O2
-Molecular Weight: 260.26
-Boiling point: About 220-225 degrees Celsius
-Melting point: About -45 degrees Celsius
-Density: About 1.12 g/mL
This compound is mainly used in the field of organic synthesis, specific uses include:
-as an intermediate for anti-cancer drugs
-for the synthesis of biologically active molecules
-For the preparation of organic chemicals such as pharmaceuticals and pesticides
The compound can be prepared by the following methods:
1. The first tert-butyl carbamate and oxygen fluorination agent reaction, the introduction of a fluorine atom.
2. The resulting product is reacted with copper difluorosulfate (CuF2) to introduce a second fluorine atom.
3. Finally, the reaction product is subjected to alkaline hydrolysis to obtain the target compound.
Regarding safety information, this compound should be handled and stored in accordance with safe operating procedures. It can be irritating and is a risk to the eyes, skin and respiratory tract. Therefore, contact should be avoided during use and necessary personal protective equipment should be provided. At the same time, it should be operated in a well-ventilated area, and pay attention to the danger of fire prevention and explosion. It is best to read the relevant safety data forms before use and follow the relevant safety operation guidelines.
Last Update：2024-04-09 21:32:47